ABSTRACT The global spread of Plasmodium falciparum chloroquine resistance transporter (PfCRT) variant haplotypes earlier caused the widespread loss of chloroquine (CQ) efficacy. In Asia. novel PfCRT mutations that emerged on the Dd2 allelic background have recently been implicated in high-level resistance to piperaquine. and N326S and I356T have been associated with genetic backgroun... https://foldlyers.shop/product-category/spotlights/