In this article, we demonstrate that conolidine, a all-natural analgesic alkaloid Utilized in conventional Chinese drugs, targets ACKR3, thereby giving additional proof of the correlation among ACKR3 and soreness modulation and opening alternative therapeutic avenues with the therapy of chronic ache. All logos, registered trademarks and service-marks outlined on https://abrahamo456kxh4.bimmwiki.com/user