An interaction involving histaminergic and opioidergic units within the CNS was suggested practically thirty many years ago, via an observation that morphine administration resulted in the release of histamine and its elevated turnover during the periaqueductal gray (Nishibori, Oishi, Itoh, & Saeki, 1985), suggesting that analgesia produced by opioids https://hayleyn505ewl0.iamthewiki.com/user